Abstract

Background: Transitions of care are high-risk situations for the manifestation of medication discrepancies and, therefore, present threats for potential patient harm. Medication discrepancies can occur at any transition within the healthcare system. Methods: Fifth-year pharmacy students assessed a best possible medication list (BPML) during a medication review (based on medication history and patient interview) in community pharmacies. They documented all discrepancies between the BPML and the latest medication prescription. Discrepancies were classified using the medication discrepancy taxonomy (MedTax) classification system and were assessed for their potential clinical and economic impact. Results: Overall, 116 patients with a mean age and medication prescription of 74 (± 10.3) years and 10.2 (± 4.2), respectively, were analyzed. Of the 317 discrepancies identified, the most frequent type was related to strength and/or frequency and/or number of units of dosage form and/or the total daily dose. Although, the majority of discrepancies were rated as inconsequential (55.2%) on health conditions, the remainder posed a potential moderate (43.2%) or severe impact (1.6%). In 49.5% of the discrepancies, the current patients’ medication cost less than the prescribed. Conclusion: Community pharmacies are at a favorable place to identify discrepancies and to counsel patients. To improve patient care, they should systematically perform medication reconciliation whenever prescriptions are renewed or added.

Highlights

  • Transitions of care, especially hospital admission and discharge, are high-risk situations for the manifestation of medication discrepancies and relevant origins for potential patient harm [1,2,3].Medication discrepancy is defined as “any differences in the prescribed medication, dose, route, or frequency noted among the sources of documentation.” [4]

  • In the participating community pharmacy was inadequate for the best possible medication list (BPML)

  • Pharmacy students performed medication reconciliation in community pharmacies in patients with polypharmacy for long-term use, based on a BPML compiled through a type 2a medication review in Swiss community pharmacies

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Summary

Introduction

Transitions of care, especially hospital admission and discharge, are high-risk situations for the manifestation of medication discrepancies and relevant origins for potential patient harm [1,2,3].Medication discrepancy is defined as “any differences in the prescribed medication, dose, route, or frequency noted among the sources of documentation.” [4]. Unintentional discrepancies occur when prescribers unintentionally add, change, or remove medications from the medication list [5]. The latter type of medication discrepancies can lead to adverse drug events [5]. Transitions of care are high-risk situations for the manifestation of medication discrepancies and, present threats for potential patient harm. Methods: Fifth-year pharmacy students assessed a best possible medication list (BPML) during a medication review (based on medication history and patient interview) in community pharmacies. They documented all discrepancies between the BPML and the latest medication prescription. They should systematically perform medication reconciliation whenever prescriptions are renewed or added

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