Abstract
Background and objectives: Systemic lupus erythematosus is an autoimmune disease that involves several systems of the body. Due to the chronic nature of this disease, non-adherence with medication regimen can lead to deterioration of the disease and also misinterpretation of treatment results. The aim of this study was to determine the medication adherence of patients with Systemic lupus erythematosus.Method: In this descriptive study, medication adherence was investigated in 209 patients with SLE who were attending lupus clinic of one of the hospitals affiliated to Tehran University of Medical Sciences. The samples who had the inclusion criteria were entered into the study in a convenience and continuous manner. Then, they completed a demographic information form and MMAS-8. Data were analyzed by SPSS software using descriptive statistics, chi-square and ANOVA tests.Results: The results showed that 18.7% of patients had high adherence to medication regimen, so that 94 patients (45.0%) had low adherence and 76 patients (36.4%) had moderate level of adherence to medication. Also, there was no significant relationship between the demographic and clinical variables of patients and their medication adherence.Conclusion: Due to the low and moderate medication adherence of patients with Systemic lupus erythematosus, it is necessary to take measures to increase the medication adherence among these patients. It is also necessary to provide patient education by nurses and physicians in the clinic and to pay attention to this issue in medical and nursing programs.
Highlights
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease of a chronic nature, which has periods of recurrence and remission [1]
Analysis of the participant responses showed that 96 medication was upsetting to them and they felt bad about patients (45.93%) sometimes forgot to take their following the treatment plan (Table 2). medications, and for 121 patients (57.89%) daily use of
The results of the present study showed that 45.0% of patients had low medication adherence, 36.4% had moderate adherence, and 18.7% had high level of medication adherence
Summary
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease of a chronic nature, which has periods of recurrence and remission [1]. Involvement of different body systems causes many problems and disabilities for patients, leading to dependence and difficulty in meeting health care needs. These issues have high costs for patients [3], and impose significant costs on the health care system, especially when disease severity elevates [4]. The treatment of SLE varies depending on its stage, it must be followed for the remaining life of the patient due to its chronic nature Pain management in these patients by non-steroidal anti-inflammatory medications and weakening of the immune system by immunosuppressive medications are the most important therapeutic goals in SLE. Non-adherence to medication regimen hinders the effective management of the disease and leads to negative health outcomes, worsening of the disease, hospitalization, and even death among SLE
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