Abstract
Abstract Medical mistrust is a nuanced construct that refers to mistrust of various actors and levels of the healthcare system. This mistrust of the motives of the medical system and its actors, which is consistently higher among historically marginalized groups, acts as a barrier to engagement in several health behaviors. Its association with decreased likelihood of engaging in health behaviors, along with higher levels of mistrust being reported by historically marginalized populations, positions medical mistrust as a contributor to health disparities. Although scholarship has focused on Black Americans, there are other communities for whom this construct is thought to be influential. Alongside being a barrier to health behaviors of interest, it is both an antecedent to and outcome of communication; interpersonal communication, campaign messages, and news media can all contribute to medical mistrust. Medical mistrust stands as a barrier to engagement in health behaviors, particularly for historically marginalized communities, that can be both heightened by and potentially ameliorated by communication.
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