Abstract
Diuretics were given alone or in combination to normal subjects and cirrhotic patients with ascites. Patients unable to excrete sodium and water under basal conditions (Stage I), were found to be systematically resistant to all drugs tested. Patients with ascites and essentially normal sodium and water excretion made good diuretic responses to all drugs. Resistance of patients was overcome by the combination of thiazides and meralluride. Potassium output increased in all cases, even in the absence of satisfactory diuretic responses. Potassium supplements should therefore be given. Maintenance of relatively low water intake was of value in preventing hyponatremia. Strict low sodium intake was found essential for good over‐all results.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
