Abstract

Embryo cryopreservation improves efficiency and security of assisted reproduction techniques. Nonetheless, it can be questionable, so it must be justified from technical, legal and ethical points of view. This article analyses these perspectives. Embryo cryopreservation maximizes the probability of pregnancy, avoids new ovary stimulations and reduces the occurrence of multiple gestations. There is consensus that the in vitro embryo deserves legal protection by its own, although not as a newborn. Very few countries prohibit embryo cryopreservation based on the legal duty to protect human life since fecundation. Those countries that allow it, privilege women's reproductive rights. In Chile and in Latin America, no laws have been promulgated to regulate human assisted reproduction. The moral status of the embryo depends on how it is considered. Some believe it is a potential person while others think it is just a group of cells, but all recognize that it requires some kind of respect and protection. There is lack of information about the number of frozen embryos and their final destination. As a conclusion the authors propose that women or couples should have the right to decide autonomously, while institutions ought to be clear in their regulations. And the legislation must establish the legal status of the embryo before its implantation, the couples' rights and the regulation of the embryo cryopreservation. Personal, institutional or legal decisions must assume a concept about the moral status of the human embryo and try to avoid their destruction or indefinite storage.

Highlights

  • Embryo cryopreservation improves efficiency and security of assisted reproduction techniques

  • Embryo cryopreservation maximizes the probability of pregnancy

  • Very few countries prohibit embryo cryopreservation based on the legal duty to protect human life since fecundation

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Summary

Eficiencia de la criopreservación de embriones humanos

Las técnicas de reproducción asistida de alta complejidad con hiperestimulación ovárica controlada permiten aspirar ovocitos, seleccionarlos y realizar la fertilización in vitro clásica o la inyección intracitoplasmática de espermatozoides (ICSI). La European Society of Human Reproduction and Embriology (ESHRE) ha informado que durante el año 2008 se realizaron en Europa 405.091 ciclos de alta complejidad (FIV/ICSI), con una tasa de 20,7% de recién nacidos por ciclo iniciado. Considerando el mismo reporte, durante el mismo año hubo 97.120 ciclos de descongelación embrionaria con transferencia uterina, con una tasa de 13,7% de recién nacidos por ciclo de embriones descongelados[6]. La alternativa a la criopreservación embrionaria en ese período de estudio fue la criopreservación de los ovocitos sobrantes, reportándose tasas de recién nacido de 11,6% por transferencia[7]. Con o sin criopreservación de embriones, las tasas de recién nacidos por transferencia en el ciclo fresco son relativamente similares, la diferencia es significativa en el ciclo de descongelamiento posterior. La descongelación ovocitaria ofrece menores tasas de recién nacidos que la descongelación embrionaria (12,5% vs 16,4%, CI 95%), difiriendo también en las tasas de embarazos múltiples[8]

Visión jurídica de la criopreservación de embriones
Estatuto moral del embrión humano
Full Text
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