Abstract
Introduction:Mixed urinary incontinence (MUI) is a coexistence of both urgency urinary incontinence and stress urinary incontinence. Medical, Epidemiologic, and Social aspects of Aging (MESA) questionnaire is a validated and commonly used tool to diagnose predominant components of it and assess the severity, which can offer help in clinic. However, MESA questionnaire is still not available in China. The aim of the study is to translate English MESA questionnaire into a Chinese version, adapt it in Chinese culture, and validate the measurement properties among female patients with MUI and urgency-predominant MUI.Methods:MESA questionnaire will be translated and culturally adapted in China. The validation will be embedded in a multicentered randomized controlled trial targeted at women with urgency-predominant MUI. Apart from MESA questionnaire, 3 groups of patients are to receive clinical extended assessment, keep 3-day voiding diary, and complete International Consultation on Incontinence Questionnaire Short Form to evaluate the measurement properties of reliability and validity (internal consistence, test-retest reliability, construct validity, and responsiveness).Discussion:If MESA questionnaire is of relatively high reliability and validity in diagnosing subtypes of MUI and assessing the severity, it can help to choose more appropriate therapy for patients and simplify the workload of clinicians.Trial registration:ClinicalTrials.gov NCT03803878, January 11, 2019.
Highlights
Mixed urinary incontinence (MUI) is a coexistence of both urgency urinary incontinence and stress urinary incontinence
If MESA questionnaire is of relatively high reliability and validity in diagnosing subtypes of MUI and assessing the severity, it can help to choose more appropriate therapy for patients and simplify the workload of clinicians
The validation of Chinese language version MESA questionnaire is embedded in a 3-armed random controlled trial, with a sample of 282, to evaluate the effect of electroacupuncture VS Solifenacin on women suffering from urgency-predominant MUI
Summary
Mixed urinary incontinence (MUI) is a coexistence of both urgency urinary incontinence and stress urinary incontinence. Epidemiologic, and Social aspects of Aging (MESA) questionnaire is a validated and commonly used tool to diagnose predominant components of it and assess the severity, which can offer help in clinic. The aim of the study is to translate English MESA questionnaire into a Chinese version, adapt it in Chinese culture, and validate the measurement properties among female patients with MUI and urgency-predominant MUI. Mixed urinary incontinence (MUI) is defined as complaint or involuntary loss of urine associated with urgency and with effort or physical exertion or on sneezing or coughing.[1] It is regarded as urgency-predominant when urgency incontinence episodes dominate over stress ones and stress-predominant when stress incontinence episodes dominate.[2] The treatment of MUI often begins with the most bothersome symptoms and the YS and YL contributed to the paper, and are the first authors
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