Abstract

BackgroundOsteoarthritis (OA) can result in significant pain, requiring pain management with opioids. Medical cannabis (MC) has the potential to be an alternative to opioids for chronic pain conditions. This study investigates whether MC used in the management of OA-related chronic pain can reduce opioid utilization.MethodsForty patients with chronic OA pain were certified for MC. Average morphine milligram equivalents (MME) per day of opioid prescriptions filled within the six months prior to MC certification was compared to that of the six months after. Visual analog scale (VAS) for pain and Global Health scores were measured at baseline, three, and six months post MC certification.ResultsAverage MME/day decreased from 18.2 to 9.8 (n=40, p<0.05). The percentage of patients who dropped to 0 MME/day was 37.5%. VAS scores decreased significantly at three and six months, and Global Physical Health score increased significantly by three months.ConclusionsMC reduces opioid prescription for patients with chronic OA pain and improves pain and quality of life.

Highlights

  • The United States (US) currently faces an opioid crisis with opioid-related deaths nearly quadrupling between 1999 and 2015 and 37.8% of adults using opioids in 2015 [1]

  • Preliminary studies in patients with OA and rheumatoid arthritis have shown that the cannabinoid receptor system is present in the synovium of affected joints, providing evidence that Medical cannabis (MC) has potential for therapeutic pain management in these patients [12]

  • The study hypothesis was that MC certification and use for chronic pain from OA would result in a decrease of opioid prescriptions filled

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Summary

Background

Osteoarthritis (OA) can result in significant pain, requiring pain management with opioids. Medical cannabis (MC) has the potential to be an alternative to opioids for chronic pain conditions. This study investigates whether MC used in the management of OA-related chronic pain can reduce opioid utilization

Methods
Conclusions
Introduction
Materials And Methods
Discussion
Disclosures
Hill KP
14. Pennsylvania Department of Health
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