Abstract
AbstractA large unilocular multilobate bronchogenic cyst was found in the right superior mediastinum of a 93‐year‐old female anatomic cadaver. By reason of its location, shape, and serous membrane (pleural) coverings, it appeared to have been formed from a sequestered azygos lobe which slowly acquired alternate sources of vascu‐larization through adhesion to pericardial vessels and the arch of the azygos vein. It is postulated here that the relatively rudimentary organization of this cyst did not reflect a primitive stage of origin but was indicative of a plasticity in developing lung tissue that permitted a regression from a more advanced stage of morphogenesis when subjected to spatial restrictions; a process well demonstrated in a cited animal model. Thus, this case may illustrate that mediastinal bronchogenic cysts are not necessarily derivatives of the very early foregut components as previously proposed.
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