Abstract
The efficacy of Trental (pentoxifylline) in the treatment of intermittent claudication was evaluated in 14 double-blind randomized studies, involving 475 patients with chronic occlusive vascular disease. In twelve studies which were performed in the USA, different countries of Europe and Australia, a placebo was used as control. Low doses of adenosine or nylidrine respectively, were given to the control groups in the other two studies. A total of 238 patients were allotted to Trental and 237 to the control groups. In most studies, the recommended dosage of Trental was 3 X 400 mg pentoxifylline in sustained release tablets. Twelve of the 14 trials had a duration between 8 and 24 weeks. The efficacy of Trental was established in a reproducible manner through the trial series under different trial designs following the requirements and guidelines from local authorities and medical societies. The number of patients with an improvement in walking distance of more than 100% was four times higher in the Trental group compared with the control group. The superiority of the Trental treatment over the control's persisted also when taking into account risk factors such as diabetes, hypertension, smoking habits and duration of the disease.
Highlights
Doctors are in a unique position of respect and power in the society
Even foreign examiners appreciated the medical education and examination conduction system as well as the service given by doctors through so many obstacles in this country
It is not that they haven’t the quality or ability rather it is their affectionate love for the country people and patriotism which makes them do so
Summary
Doctors are in a unique position of respect and power in the society. Hippocrates suggested that doctors may influence patients’ health. Doctor’s communication and interpersonal skills encompass the ability to gather information in order to facilitate accurate diagnosis, counsel appropriately, give therapeutic instructions, and establish caring relationships with patients.[2] In many foreign countries doctors of Bangladesh are playing important roles in the health sector by virtue of their quality. Even foreign examiners appreciated the medical education and examination conduction system as well as the service given by doctors through so many obstacles in this country.
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