Abstract
The instrument MEDAPP Medical Applications), operated by the Technische Universität München, and the respective irradiation position are located at the world-wide unique fast neutron beam tube SR10 to which a uranium converter is attached. Thus, the instrument is operated with unmoderated fission neutrons and can be used for a broad variety of applications. For selected tasks, an alternative use with thermal neutrons is possible.
Highlights
MEDAPP is an instrument primarily built for the medical treatment of malignant tumours; but the irradiation room can be used for general purposes, e.g. for biological research and technical irradiations
Due to their energy spectrum, fast reactor neutrons have the highest biological e ectiveness of clinical neutron beams used in cancer treatment, comparable only to the e ectiveness of heavy ions
This advantage comes at the expense of penetration depth in tissue, which - due to the relatively low energy of 2 MeV - limits the application of fast reactor neutrons to near-surface tumours, typically recurrent breast tumours and melanomas
Summary
MEDAPP is an instrument primarily built for the medical treatment of malignant tumours; but the irradiation room (see Figure 1 and 2) can be used for general purposes, e.g. for biological research and technical irradiations. Due to their energy spectrum, fast reactor neutrons have the highest biological e ectiveness of clinical neutron beams used in cancer treatment, comparable only to the e ectiveness of heavy ions. This advantage comes at the expense of penetration depth in tissue, which - due to the relatively low energy of 2 MeV - limits the application of fast reactor neutrons to near-surface tumours, typically recurrent breast tumours and melanomas.
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