Abstract
High radioactive concentration of 131I in the form of 131I[NaI] solution is essential for preparation of large-dose therapeutic capsules used in the management of thyroid cancer. In this communication, we report the synthesis of mesoporous alumina sorbent (surface area = 292 ± 28 m2/g, mean pore diameter = 6.8 ± 0.7 nm) by a novel solid state mechanochemical approach and its utilization in post-processing concentration of 131I. The overall yield of 131I after the concentration procedure was >90% and 131I[NaI] solution could be obtained with appreciably high (1.7 TBq/mL) radioactive concentration, suitable for use in nuclear medicine. The promising results obtained in this study would stimulate greater utilization of this new class of sorbents in sample preparations by solid phase extraction procedures for societal benefits.
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