Abstract

1. Excitability of the electrically excitable membrane of the cortical neuron changes regularly in the course of habituation to a repetitive stimulus. 2. Excitability of the trigger zones of the spontaneous AP increases nonspecifically, due to nonspecific depolarization of the membrane. 3. Excitability of the trigger zones of AP evoked by a monotonic stimulus and an extrastimulus changes in opposite directions. The critical level of depolarization of AP in response to a monotonic stimulus shifts in the positive direction, and its threshold potential rises. The critical level of depolarization of AP in response to an extrastimulus shifts in the negative direction and its threshold potential falls. 4. Lowering of the excitability of the trigger zones generating AP in response to a monotonic stimulus and the increase in excitability of zones participating in AP generation in response to an extrastimulus are the postsynaptic mechanism of habituation of the electrically excitable membrane of the cortical neuron. 5. Changes in the electrogenic properties of the trigger zones of evoked AP are the probable cause of functional lability of the excitability of these zones during habituation.

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