Abstract
The review deals with the description of the mechanisms involved in the formation of kidney fibrosis. Presented molecular factors activation of the pathological process, signaling pathways, competent cells with synthetic provospolitelnyh mediators, the role of epithelial-mesenchymal transition in the development and progression of renal fibrosis. Demonstrated evidence of the importance of the remodeling of the renal arteries of small diameter in the development and progression of renal fibrosis tissue. Sources of information on topics Review article full disclosure, a presentation of the current views on the study of this problem, use the database PubMed citations, RISC, Scopus, Web- Mathematical Sciences, Google Scholar, Copernicus index, Ulrich Periodicals Directory.
Highlights
The review deals with the description of the mechanisms involved in the formation of kidney fibrosis
The Resistive Index Is a Marker of Renal Function, Pathology, Prognosis, and Responsiveness to Steroid Therapy in Chronic Kidney Disease Patients
Summary
The review deals with the description of the mechanisms involved in the formation of kidney fibrosis. Presented molecular factors activation of the pathological process, signaling pathways, competent cells with synthetic provospolitelnyh mediators, the role of epithelial-mesenchymal transition in the development and progression of renal fibrosis. Происходящих при ХПН, позволяет проводить адекватную терапию, направленную на замедление ремоделирования почек, а также выполнять диагностический поиск, уточняющий тяжесть повреждения почечной ткани.
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