Abstract
WE report new findings on the chemically-induced fusion of hen erythrocytes and discuss possible ways in which the lipid and protein/glycoprotein components of membranes may behave during the process of membrane fusion. Our observations are consistent with Poste and Allison's1 idea that the aggregation of intrinsic membrane proteins is important in membrane fusion but we suggest that fusion may occur in regions of perturbed lipid bilayer which are thus denuded of intramembranous particles.
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