Abstract

Neisseria meningitidis is known as the leading cause of bacterial meningitis worldwide, and understanding the mechanisms by which N. meningitidis evades host immunity is crucial. The innate immune system is vital for protecting individuals against pathogens. However, N. meningitidis has evolved multiple mechanisms to avoid killing by human antimicrobial peptides, complement system, phagocytic cells, and so on. Bacterial structures such as polysaccharide capsule and those which mimic or bind host molecules play an important role in N. meningitidies colonization and invasion. Here, we provide an update on the recent findings on . the diverse mechanisms by which N. meningitidis avoids human innate immune system. Key words: Neisseria meningitidis; Innate immune system; Avoid; Mechanism

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