Abstract

Studies on the regulation of genetic expression in mammalian systems have demonstrated that a significant amount of regulation occurs at the level of genetic translation. Studies in this report demonstrate that it is possible to measure the specific lifetime for a mRNA of a hepatic enzyme. Furthermore, the enzyme under study, serine dehydratase, was found to exist in two isozymic forms, the synthesis of each form apparently being regulated by different mechanisms. Such findings are in line with other studies in this area and demonstrate the complexity of the regulation of genetic expression in mammalian systems wherein one is dealing with multiple phenotypic populations of cells as opposed to prokaryotes which are self-sufficient.

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