Abstract

The lifespan of the corpus luteum is influenced and can be manipulated by mechanisms (and their interactions) associated with secretions from the pituitary, ovary, uterus and conceptus. Luteal lifespan and secretion of progesterone are controlled by mechanisms which may enhance (luteotropic) or cause the demise (luteolytic) of the corpus luteum. Mechanisms controlling luteal function may be different among species. In addition, luteal function in some species has been characterized by subnormal function, either corpora lutea with short lifespans or corpora lutea with normal lifespans but decreased secretion of progesterone. Endocrine and cellular mechanisms which are associated with control of normal and subnormal luteal function in livestock species are discussed in this review.

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