Mechanisms and Energetics of Protein/Peptide Interactions in Biological Membranes

Abstract

Understanding the delicate balance of forces governing helix/β-hairpin interactions in transmembrane proteins is central to understanding membrane structure and function. These membrane constituent interactions play an essential role in determining the structure and function of membrane proteins, and protein interactions in membranes, and thus form the basis for many vital processes, including transmembrane signaling, transport of ions and small molecules, energy transduction, and cell-cell recognition.