Abstract

Experiments on cats showed that interhemispheric generalization of strychnine seizure potentials from the orbitofrontal cortex takes place mainly by the callosal route. Unlike other projection and association areas of the cortex, not the whole of the corpus callosum but only its anterior part (genu and rostrum) participates in the transmission of strychnine spikes. The results agree with the general concept of the determinant dispatch station (DDS) in the integrative activity of the nervous system. They show that DDS formation induces secondary foci of excitation which exactly reproduce the pattern of activity of the DDS. Removal of these “mirror” foci, which behave as “destination stations,” from the influence of DDS leads to abolition of the activity induced in them.

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