Abstract

The present study indicated that the repeated exposure of thelaboratory strain of the house fly, Musca domestica (Linnaeus) toCypermethrin, Imidacloprid and Spinosad lead to developing resistanceagainst these insecticides. The resistance level of the selected strainsreached after 30th generation to 24.8, 15.53 and 9.56 folds forCypermethrin, Imidacloprid and Spinosad compared with the laboratorystrain.This study also showed the breakdown of resistance usinginsecticide binary mixtures, where the mixture of Cypermethrin+Imidacloprid exhibited potentiation at the ratio of 1:1 and 1:2 against allthe resistant strains. Also, the combination of Cypermethrin withSpinosad gave potentiation at the ratios of 1:1, 1:2 and 2:1 againstImidacloprid and Spinosad resistant strains.

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