Abstract
Chronic exposure of rats to low doses of cadmium chloride (CdCl2) results in accumulation of cadmium in the liver, followed by kidney damage (Dudley et al. 1985). It has been proposed that cadmium-metallothionein complexes released from the liver cells provoke kidney damage by lysosomal breakdown of these complexes in the proximal tubule cells of the kidney (Dudley et al. 1985).
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