Abstract

Cyclophilin A (CypA) is found to be highly expressed in different kinds of tumor cells, which could regulate the occurrence and development of many kinds of tumor through multiple signal transduction pathways such as inducing the formation of inflammatory carcinoma, accelerating the transcription cycle of tumor cells, promoting the invasion and metastasis of tumor cells, inhibiting the apoptosis of tumor cells and reducing the sensitivity of tumor cells to chemotherapy drugs. It suggests that CypA might be considered as a kind of oncogene, which is expected to be a novel target for tumor treatment. Key words: Neoplasms; Cyclophilin A; Molecular mechanisms of pharmacological action

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.