Abstract
In the rat liver microsome-reduced nicotinamide-adenine dinucleotide phosphate system, the thionosulphur of Dyfonate ® ( O -ethyl S -phenyl ethylphosphonodithioate) is replaced by oxygen from atmospheric molecular oxygen, producing the oxon analog, a potent anticholinesterase; however, in the same system, cleavage of the ester bond also occurs to form a non-toxic thiophosphonic acid derivative, incorporating oxygen from water, only. There is evidence that these reactions involve a common intermediate, a mechanism probably applicable to other thionophosphorus insecticide chemicals.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
