Abstract
Data from a previous study were used to obtain correlations between log mean pore diameter and porosity of tablets. Cornstarch appears to modify this relationship of mean pore diameter and porosity in magnesium oxide and magnesium trisilicate tablets. Dilution of salicylamide with cornstarch and aspirin by three different disintegrants (cornstarch, cation‐exchange resin, and waxy maise starch) had little effect on this relationship. The one exception was 10% cationic‐exchange resin‐90% aspirin mixture. The equation, log y = mX + b, where y is the mean porediameter and X the porosity, can be used to calculate the mean pore diameter from the more easily obtained porosity.
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