Abstract
Background: Left ventricular (LV) torsion may be a potential marker for LV systolic function at rest but changes in torsion during stress echocardiography have not been extensively studied. Aim: To determine changes in the magnitude and timing of LV torsion during dobutamine stress echocardiography (DSE). Methods: Twenty-five patients (36% male, age 65.6 ± 15.0 years) underwent DSE as per clinical protocol. Echocardiographic images were acquired using Vivid E9 (GE-Vingmed, Horten, Norway) at rest, low dose, and peak dose dobutamine infusion. Ejection fraction (EF), wall motion score index (WMSI), peak torsion (apical rotation minus basal rotation), and time to peak torsion from onset of systole were measured offline using EchoPAC BT09, GE-Vingmed. Results: ANOVA analysis was performed and the results are tabulated below as mean ± SD.Tabled 1BaselineLow dosePeak doseP valueEF (%)58.0 ± 11.869.0 ± 14.469.6 ± 15.90.0069WMSI1.18 ± 0.371.14 ± 0.291.18 ± 0.270.853Torsion (degrees)19.3 ± 8.822.8 ± 9.522.4 ± 9.80.364Time (ms)374.8 ± 55.7294.1 ± 74.3206.3 ± 43.3<0.0001 Open table in a new tab Conclusions: The time to peak torsion was significantly reduced during DSE and correlated with increase in EF. However, there was no significant change in the magnitude of torsion. Timing may be a more important parameter than magnitude, but further studies will be needed to determine the clinical significance.
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