Abstract
Microtubules are the most rigid cytoskeletal filaments, providing structure to the cell, the path for intracellular transport, and the machinery of the mitotic spindle. To perform these functions in the cell, the microtubule must be rigid yet dynamic. Both their rigidity and dynamicity are controlled by microtubule associated proteins (MAPs). We characterized the effects of MAP4 and the EBs on microtubules mechanics and dynamics in vitro.
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