Mechanical systolic dyssynchrony assessed with 3-D echocardiography and its association with global strain

Abstract

Abstract Background The evaluation of global longitudinal strain using 2-D velocity vector imaging, is an accurate automatized tool for assessment of ventricular function, nevertheless its correlation with systolic synchrony by 3D echocardiography, remains unclear. Aims To evaluate the correlation between global longitudinal strain and systolic synchrony index (SSI). In addition, identify which ventricle has the global longitudinal strain with the best odds ratio for detecting systolic dyssynchrony (SSI ≥6.0 ms). Methods We evaluate left (LV-GS, LA-GS) and right (RV-GS; RA-GS) global longitudinal strain using automatized 2-D velocity vector imaging. SSI was measured using 17 segments according to guidelines. Results We included 420 subjects. Characteristics of study population are presented in table 1. We found a positive and significant correlation with LV-GS (r=0.152, 95% CI: 0.052–0.247), RV-GS (r=0.119, 95% CI: 0.02–0.215), LA-GS (r=0.160, 95% CI: 0.290,0.212) and RA-GS (r=0.249, 95% CI: 0.355,-0.136) (Figure 1). Decreased values of RV-GS (OR: 1.06, 95% CI: 1.01–1.10) had the better association with mechanical systolic dyssynchrony after adjusted for covariates. Conclusion Automated measurement of the global longitudinal deformation of the left and right chambers correlates with the systolic synchrony index. The quantification of RV-GS could be an ideal tool to detect systolic dyssynchrony using an automated approach Funding Acknowledgement Type of funding source: None