Abstract
Transfection In article number 2103198, Andy Tay and Nicholas Melosh illustrate the use of high aspect-ratio hollow nanostructures coupled with transient electroporation for electrophoretic delivery of DNA into T cell. Magnetic stimulation was added subsequently to enhance intracellular DNA transport towards the nucleus to achieve high transfection efficiency. Facilitated by magnetic manipulation, the whole gene delivery process is centrifuge-free, making it compatible with end-to-end cell manufacturing.
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