Abstract
Prosthetic valve thrombosis (PVT) is a serious complication in the left-sided heart valve. However, in the right-side position, this complication may be completely asymptomatic or accompanied by only a few symptoms. Research on the prevalence of thrombosis in right-sided valves is still insufficient. We sought to retrospectively report our center’s experience concerning PVT and its management outcomes.
Highlights
Prosthetic valve thrombosis (PVT) is a serious complication in the left-sided heart valve
Thrombolytic therapy is an effective treatment for PVT and its recurrence
While the PVT incidence is higher for right-sided mechanical valves than left-sided mechanical valves, [5,17,15, 18] there is a paucity of large-scale studies regarding the prevalence of rightsided PVT
Summary
Prosthetic valve thrombosis (PVT) is a serious complication in the left-sided heart valve. Prosthetic valve thrombosis (PVT) is a serious complication, for left-sided heart valves; it is unprecedented within the aortic and mitral positions [1-3]. For the right-sided position, bioprosthetic valves are generally preferred to mechanical valves [4-6]. Reports have emerged concerning the degeneration of bioprosthetic valves in the pulmonary position, leading to a higher interest in the use of mechanical valves in the right-sided position [9]. The occurrence of thrombosis within the tricuspid or pulmonary valve is not as alarming as that in the left-sided valve, with the event even having no symptoms in some patients. 10 It appears that thrombosis is far from uncommon in the right-sided valve; studies have reported a prevalence rate of between 12% and 15% [10,11]. According to the latest guideline of the American College of Cardiology/American Heart Association (ACC/AHA) vis-à-vis the management of patients with valvular diseases, PVT is managed by slow-infusion, low-dose fibrinolytic therapy [12]
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