Abstract
1. 1. The mechanical properties of sartorii muscles from the toad Xenopus borealis were studied in organ cultures lasting up to 26 days. 2. 2. Isometric twitch and tetanic tensions diminished in force reaching half their initial values after 15 days in culture. In contrast, twitch time to peak time to half relaxation, twitch-tetanus ratio and muscle weight-body weight ratio, were unchanged. 3. 3. Maximum isotonie shortening velocity ( V max) declined, with a half time similar to that of the isometric force. 4. 4. The fall in isometric tension is probably due to a breakdown of activation in some fibres. The change in V max could be due to a loss of functional sarcomeres in series with the tendons.
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