MECHANICAL CHARACTERIZATION OF ANIMAL DERIVED GRAFTS FOR SURGICAL IMPLANTATION

Abstract

Bioprostheses obtained from animal models are often adopted in abdominal surgery for repair and reconstruction. The functionality of these prosthetic implants is related also to their mechanical characteristics that are analyzed here. This work illustrates a constitutive model to describe the short-term mechanical response of Permacol[Formula: see text] bioprostheses. Experimental tests were developed on tissue samples to highlight mechanical non-linear characteristics and viscoelastic phenomena. Uni-axial tensile tests were developed to evaluate the strength and strain stiffening. Incremental uni-axial stress relaxation tests were carried out at nominal strain ranging from 10% to 20% and to monitor the stress relaxation process up to 400[Formula: see text]s. The constitutive model effectively describes the mechanical behavior found in experimental testing. The mechanical response appears to be independent on the loading direction, showing that the tissue can be considered as isotropic. The viscoelastic response of the tissue shows a strong decay of the stress in the first seconds of the relaxation process. The investigation performed is aimed at a general characterization of the biomechanical response and addresses the development of numerical models to evaluate the biomechanical performance of the graft with surrounding host tissues.