Measuring the pons: a non-invasive biomarker for pediatric diffuse intrinsic pontine glioma.

Abstract

CNS OncologyVol. 3, No. 3 EditorialMeasuring the pons: a non-invasive biomarker for pediatric diffuse intrinsic pontine gliomaKatherine E WarrenKatherine E WarrenSearch for more papers by this authorPublished Online:17 Jun 2014https://doi.org/10.2217/cns.14.10AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInReddit View articleKeywords: biomarkerbrainstem gliomaDIPGresponsetumor measurementReferences1 Smith M, Seibel N, Altekruse S et al. Outcomes for children and adolescents with cancer: challenges for the twenty-first century. J. Clin. Oncol. 28(15), 2625–2634 (2010).Crossref, Medline, Google Scholar2 Ostrom Q, Gittleman H, Farah P et al. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2006–2010. Neuro-oncology 15(Suppl. 2), ii1–ii56 (2013).Crossref, Medline, Google Scholar3 Van Den Bent M, Vogelbaum M, Wen P et al. End point assessment in gliomas: novel treatments limit usefulness of classical Macdonald's criteria. J. Clin. Oncol. 27, 2905–2908 (2009).Crossref, Medline, Google Scholar4 Warren K, Poussaint T, Vezina G et al. Challenges with defining response to antitumor agents in pediatric neuro-oncology: a report from the response assessment in pediatric neuro-oncology (RAPNO) working group. Pediatr. Blood Cancer 60(9), 1397–1401 (2013).Crossref, Medline, Google Scholar5 Macdonald D, Cascino T, Schold S et al. Response criteria for Phase II studies of supratentorial malignant glioma. J. Clin. Oncol. 8, 1277–1280 (1990).Crossref, Medline, CAS, Google Scholar6 Hayward R, Patronas N, Baker E, Vezina G, Albert P, Warren K. Inter-observer variability in the measurement of diffuse intrinsic pontine gliomas. J. Neurooncol. 90, 57–61 (2008).Crossref, Medline, Google Scholar7 Hargrave D, Chuang N, Bouffet E. Conventional MRI cannot predict survival in childhood diffuse intrinsic pontine glioma. J. Neurooncol. 86, 313–319 (2008).Crossref, Medline, Google Scholar8 Hipp S, Steffen-Smith E, Hammoud D, Shih J, Bent R, Warren K. Predicting outcome of children with diffuse intrinsic pontine gliomas using multiparametric imaging. Neuro-oncology 13(8), 904–909 (2011).Crossref, Medline, Google Scholar9 Steffen-Smith E, Shih J, Hipp S, Bent R, Warren K. Proton magnetic responance spectroscopy predicts survival in children with diffuse intrinsic pontine glioma. J. Neurooncol. 105, 365–373 (2011).Crossref, Medline, Google Scholar10 Dancey J, Dobbin K, Groshen S et al. Guidelines for the development and incorporation of biomarker studies in early clinical trials of novel agents. Clin. Cancer Res. 16(6), 1745–1755 (2010).Crossref, Medline, CAS, Google Scholar11 Biomarkers Definition Working Group. Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin. Pharmacol. Ther. 69, 89–95 (2001).Crossref, Medline, Google Scholar12 Russell M, Young A, Karri S. Biomarkers of pediatric brain tumors. Front. Pediatr. 1, 7 (2013).Crossref, Medline, Google Scholar13 Steffen-Smith E, Baker E, Venzon D, Shandilya S, Bent R, Warren K. Measurements of the pons as a biomarker of progression for pediatric DIPG. J. Neurooncol. 116, 127–133 (2014).Crossref, Medline, Google Scholar14 Ballester L, Wang Z, Shandilya S et al. Morphologic characteristics and immunohistochemical profile of diffuse intrinsic pontine gliomas. Am. J. Surg. Pathol. 37(9), 1357–1364 (2013).Crossref, Medline, Google ScholarFiguresReferencesRelatedDetailsCited ByAberrantly expressed microRNAs and their implications in childhood central nervous system tumors3 December 2019 | Cancer and Metastasis Reviews, Vol. 38, No. 4 Vol. 3, No. 3 Follow us on social media for the latest updates Metrics Downloaded 64 times History Published online 17 June 2014 Published in print May 2014 Information© Future Medicine LtdKeywordsbiomarkerbrainstem gliomaDIPGresponsetumor measurementFinancial & competing interests disclosureThis research was supported in part by the part by the Intramural Research Program of the National Institutes of Health, National Cancer Institute, Center for Cancer Research. The author has no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.No writing assistance was utilized in the production of this manuscript.PDF download