Abstract

The premature birth rate in Korea has increased from 13.5% in 2008 to 15.7% in 2013. The complications of premature birth are a major determinant of neonatal mortality and morbidities. The purpose of this study was to estimate the burden of premature birth in Korea using disability-adjusted life years (DALY). DALY consists of years of life lost (YLL) and years lost due to disability (YLD). In this study, preterm birth complications refer to nine diseases: P07, P22, P25, P26, P27, P28, P52, P77, P612, and H351 (International Classification of Diseases—10th Revision). YLL was calculated using mortality data from the 2012 National Health Insurance Data. YLD is a function of the prevalence, disability weight (DW), and duration of each complication. DW was determined by the Korean Disability Weight Study for National Burden of Disease in Korea 2013/2015. The burden of premature birth in Korea is 79,574 DALY (YLL: 43,725; YLD: 35,849). The burden for men (DALY: 43,603; YLL: 24,004; YLD: 19,599) is higher than that of women (DALY: 35,970; YLL: 19,720; YLD: 16,250). This study could provide essential data for evaluating the effects of policies intended to reduce preterm birth.

Highlights

  • Preterm birth is defined as giving birth earlier than 259 days since the last menstrual period or before 37 weeks of gestation [1]

  • The causes of preterm birth complication were based on the hierarchical disease cause list from the Global Burden of Disease (GBD) 2010 study [18]

  • Thesein results suggest thatinthe burden. These results suggest that the burden of disease caused by preterm birth complication in children disease caused by preterm birth complication in children has been underestimated

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Summary

Introduction

Preterm birth is defined as giving birth earlier than 259 days since the last menstrual period or before 37 weeks of gestation [1]. There are multiple known causes of preterm birth, including multiple births, polyhydramnios, an incompetent cervix, anomaly of the uterus, hypertensive disorders of pregnancy, infection, and pregnancy-related complications [2]. In the United States, the frequency of childbirth in women aged 35 years or older has increased from 5% in 1970 to 13% in 2000 [3]. The average age at first childbirth in Sweden rose from 25.9 years in 1970 to 28.9 years in 2000 [4]. The frequency of childbirth in South Korean women aged years or older has dramatically increased from 5% in 1996 to 14% in 2008 [5]

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