Abstract

The research was aimed at formulation of scientific groundings for activities on improvement of organization of medical assistance for patients with respiratory chlamydiosis of upper respiratory tract based upon intra­family infection. The laboratory research methods included identification of two types of Chlamydia: Chlamydia Pneumoniaе and Chlamydophila Trachomatis. To identify Chlamydia infection in organized population we used such method as direct immunofluorescent analysis. To verify Chlamydia infection in ENT­patients and their family members we used two direct tests simultaneously (direct immunofluorescent analysis and polymerase chain reaction) and one indirect test of immune enzyme analysis. The article presents the data on the prevalence of Chlamydia infection of nasal and pharynx mucosa in different populations: in organized children and adults, and in patients who underwent in-patient treatment of the diseases of nose, paranasal sinuses and nasopharynx resulted from insufficiency of out-patient medical care. We revealed the association of Chlamydia infection with the possibility of occurrence of acute and chronic pathology in children as well as chronic pathology in adults with breakdown by separate nosological forms. We found out that the presence of Chlamydia-infected ENT patient in a family provokes intra-family distribution of the infection. We present the structure of infection contamination of family members and the specific features of manifestation of family respiratory Chlamydiosis. We have substantiated the necessity of the measures, aimed at improvement of medical assistance for patients with respiratory Chlamydiosis from scientific viewpoint and worked out a program, determining the prioritized directions of the disease morbidity decrease. Therefore, implementation of the program aimed at optimization of providing medical care to patients with Chlamydia infection of upper respiratory tract will enable preventing the prevalence of respiratory Chlamydiosis, including the elimination of intra family centers of infection and reducing of social and economic consequences of Chlamydiosis.

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