Measurements and simulations of light-activated matter.

Abstract

Non-equilibrium active matter consumes energy to form self-organizing structures. For example, microtubules and motors assemble to form polar and nematic structures that facilitate cell division. Here, we investigate properties of varying aster geometries during and after contraction. Experiments, agent-based simulations, and field-based simulations provide insights into an in-vitro, light-activated system of microtubules (MTs) and kinesin motors. Using an agent-based simulation, we modeled the contraction process and computationally created radially symmetric aster structures; simulation results show asters contract faster at higher motor speeds and lower unbinding rates. Furthermore, the agent-based simulation captures 3D MT flux, potentially providing insight into field-based equations describing contraction. We aim to compare experimental contraction with a model from computational MT flux data, searching for mechanics that govern the formation and stabilization of aster structures.