Abstract

The pattern of the activatory inputs that control the spontaneous in vitrocontraction of the rat uterine horn is investigated. A mathematical model is used in this study. The model gives the time course of intraluminal pressure, longitudinal force, and wall morphology, when the mechanical parameters and the activatory inputs of the two muscular layers of the wall are assigned. The mechanical parameters of the smooth muscle tissue are deduced from the mecasured force-length and the force-velocity data of the myometrial tissue. The possibility of determining uniquely, from the experimental data of pressure and force, the parameters that characterize the model input is investigated. The results of the estimation of these parameters from a set of experimental data is presented.

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