Abstract
A method is described in which, by the use of radioiodine techniques, thyroid function of unanaesthetized pigeons was studied. Maximum accumulation of I131 in the pigeon thyroid was accomplished within 24 hours or less followed by rapid thyroidal-I131 release. (Average biological half-life of 2.73 ± .3 days.) Estimation of thyroid secretion rate (TSR) was then made for each pigeon by injecting graded doses of l-thyroxine until the level was reached which suppressed thyrotropic hormone secretion and thus prevented further thyroidal-I131 output. Individual TSR ranged from 1.0–2.5 µg/100 gm/day with an average for 35 adult common pigeons of 1.94 ± .07 µg/100 gm/day l-thyroxine. Analyses of correlation coefficients indicated a significant negative correlation existed between TSR and biological half-life of thyroidal-I131. Nonsignificant correlations existed between TSR and 24-hour I131 uptake and between TSR and body weight. The level of thyroid hormone secretion did not influence the pigeons' crop-sac response to standard lactogenic hormone.
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