Abstract

Skin injuries may occur when radiation doses to the skin exceed 2Gy. This study aimed to measure changes in skin microcirculation in patients undergoing chronic total occlusion percutaneous coronary interventions (CTO-PCI). In 14 patients, peak skin dose (PSD) was estimated with radiographic films and skin microcirculation was assessed with laser speckle contrast imaging (LSCI), before, 1 day after the intervention, and 4-6weeks later. The mean PSD was 1.8±0.9Gy. Peak skin microcirculation increased by 12% from 45±6 PU before to 50±9 PU 1 day after the intervention (p=0.01), and returned to 46±8 PU after 4-6weeks (p=0.15). There was no significant correlation between PSD and the change in perfusion, neither 1 day (r=-0.13, p=0.69) nor 4-6weeks after the intervention (r=0.33, p=0.35). These results suggest that there are no radiation-induced microvascular changes in the skin after CTO-PCI at skin doses below 2Gy.

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