Measurement of rabies antibody: comparison of the mouse neutralization test (MNT) with the rapid fluorescent focus inhibition test (RFFIT)

Abstract

A rapid fluorescent focus inhibition test (RFFIT) was compared with the mouse neutralization test (MNT) for measuring rabies antibody. The RFFIT was found to be the more sensitive, reproducible and accurate of the two. Considering these attributes and the convenience of the test, the conclusion is reached that RFFIT should be substituted for MNT for measurement of rabies antibody.