Abstract
The effects of storage and freeze-thawing on polyethylene glycol 4000 (PEG 4000) and14C PEG 4000 in a solution of NaCl (150 mmoles/l) containing varying amounts of human albumin were studied. Results showed that the analysis of both PEG 4000 and14C PEG 4000 is likely to be inaccurate in these fluids if the specimens have been freeze-stored, thawed and refrozen several times during a period of several weeks. This seems to be due to the freeze-thawing process itself rather than the actual storage. The amount of protein in the samples may increase the fall in estimated levels of polyethylene glycol observed.
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