Abstract
OBJECTIVE: Respiration is a useful parameter for evaluating embryo quality as it provides important information about metabolic activity. The scanning electrochemical microscopy (SECM) measuring system provides a non-invasive, simple, accurate, and consistent measurement of the respiration activity of single human embryos. In this study, we examined the clinical efficacy for IVF-elected single embryo transfer (eSET) patients using the SECM measuring system. DESIGN: prospective randomised study. MATERIALS AND METHODS: A total of 68 IVF-eSET patients were treated under the prospective randomized schedule at our private clinic. After morphological evaluation by the Veeck's method, oxygen consumption by individual human embryos was quantified by SECM measuring system. A single embryo, based on conventional morphological evaluation or morphological evaluation plus measuring the oxygen consumption rate, was elected by either decision and transferred. RESULTS: Among the cycles (N=72) that embryos showed morphologically exactly same grade by Veeck's method, the pregnancy rate in cycles with an embryo elected based on morphological evaluation plus measuring the oxygen consumption rate had a significantly higher pregnancy rate of 50.0%(18/36). compare with an embryo elected by conventional morphological method was 25.0%(9/36). Further more, the abortion rate of the oxygen measured group(5.6% 1/18) was less than the conventional group(22.2% 2/9). Finally, on-going pregnancy rate was significantly higher in the oxygen measured group(47.2% 17/36) than the conventional morphological method group(19.4% 7/36). CONCLUSION: The results of this study, indicated the high pregnancy rate and low abortion rate will come to fruition by electing the best embryo by morphological evaluation plus measuring the oxygen consumption rate in IVF-eSET. It is hoped that this new, novel method will prove to be more effective for IVF treatment.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
