Abstract
Abstract Purpose To illustrate the implantation technique & tolerance of a novel wireless silicone‐encased intraocular pressure transducer in rabbit eyes. The device can conceivably provide a reliable way to measure the IOP in situations where measurement is difficult with the present technology, for instance in eyes with keratoprosthesis implants. Methods The transducer, manufactured by Mesotec GmbH (Hannover, Germany), is a fully digital ultra miniature system, integrating pressure sensing, data handling and telemetry on a single microchip. The microchip is connected to a telemetry coil and requires no internal power source. The data is received using an external reader unit. The transducers were initially tested for calibration in enucleated bovine eyes. They were sterilized with ethylene oxide. They were implanted either through a corneal autograft (n=2) or through a large limbal incision (n=2) and placed either in the sulcus (n=2) or suspended into the vitreous cavity (n=2) after removing the crystalline lens. In one rabbit (SHAM), the crystalline lens was removed but no implant was placed. The eyes were closed with interrupted 10‐0 nylon sutures. Daily observations and weekly full clinical examinations were performed. The readings obtained by the transducer‐readers were compared with those obtained by Tonopen. Results The transducers were well tolerated, with minimal transient post‐operative intraocular inflammation that was similar in both the experimental and SHAM groups at comparable time‐points. The pressure obtained by the transducers showed good correlation with those obtained by Tonopen. Conclusion Our animal studies show that the transducer can be easily implanted and is well tolerated inside the rabbit eye, up to 4 months at the present time.
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