Abstract
SummaryThe vitamin D dependent intestinal calcium‐binding protein (calbindin‐D9K) was measured by an enzyme‐linked immunoadsorbent assay in small intestinal biopsy specimens from 10 children (aged 15–126 months). The aim was to study the relationship between calcium‐binding protein and age, bone age, and height. The patients were examined due to complaints of chronic diarrhea, but no evidence of malabsorption was found. The amount of calbindin‐D9K per mg of soluble protein in the small intestinal biopsy specimens was higher than previously studied in normal adults. Calbindin‐D9K correlated inversely with chronological age, bone age, and height of the children (p = −0.87, p = −0.66, and p = – 0.66; p < 0.05). A direct correlation was found between calbindin‐D9K and intestinal alkaline phosphatase activity (p = 0.60; p < 0.05). The decline in calbindin‐D9K may indicate that the active vitamin D dependent intestinal calcium absorption decreases during childhood.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of Pediatric Gastroenterology and Nutrition
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
