Measurement of 0 to 2 age normal eyeball volume by the use of multidetector computed tomography

Abstract

Aim: To diagnose microphthalmia or macrophthalmia, it is necessary to know the normal reference values of the eyeball volumes. However, we do not have a table of normal reference values to evaluate normal eyeball volume at 0-2 years of age. To compensate for this deficiency, we aimed to detect normal eyeball volumes in the age group of 0-2 years with multidetector computed tomography (MDCT).
 Material and Method: A total of 90 patients who underwent MDCT with a prior diagnosis of head trauma but without traumatic pathology were included in the study. Patients were divided into age groups of 0-1 months, 2-6 months, 7-12 months, 13-24 months. The mean values of patients in each age group were examined with a 95% confidence interval. The correlation between bilateral eyeball volumes and age was calculated using the Pearson correlation test. The relationship between the age groups and the volume of the eyeball was studied using one-way ANOVA test. The relationship between eyeball volumes and sex was evaluated using the Mann Whitney U test.
 Results: Mean eyeball volume was measured as 3.91±0.54 cm3 for 0-1 months, 4.44 ±0.66 cm3 for 2-6 months, 5.81 ±0.68 cm3 for 7-12 months, and 5.83±1.09 cm3 for 13-24 months. A strong positive correlation was observed between eyeball volume and age (p < 0.001). There was no statistically significant relationship between eyeball volume and sex (p > 0.05). No statistically significant difference was observed between right eyeball volume and left eyeball volume ( p> 0.05). 
 Conclusions: The increase in eyeball volume is most rapid in the first year of life. In this study, the reference eyeball volumes were determined in order to properly assess this rapid increase.