Abstract
Modelling of fields generated by therapeutic ultrasound arrays can be prone to errors arising from differences from nominal transducer parameters, and variations in relative outputs of array elements when driven under different conditions, especially when simulating steered fields. Here, the effect of element size, element positions, relative source pressure variations, and electrical crosstalk on the accuracy of modelling pressure fields generated by a 555 kHz 32-element ultrasonic array were investigated. For this transducer, errors in pressure amplitude and focal position were respectively reduced from 20% to 4% and 3.3 mm to 1.5 mm using crosstalk prediction, and experimentally determined positions.
Highlights
Ultrasonic transducers used for therapeutic applications employ multiple elements to enable focal steering, and for transcranial applications, in particular, to facilitate aberration correction and focussing in the brain.1,2 In order to perform accurate targeting and prediction of the resulting dose to the target tissues, these complex sources and the generated fields must be modelled accurately
Modelling of fields generated by therapeutic ultrasound arrays can be prone to errors arising from differences from nominal transducer parameters, and variations in relative outputs of array elements when driven under different conditions, especially when simulating steered fields
The pressure was consistently overestimated and individual differences varied between 15% and 30%, which were reduced to within 6% with crosstalk prediction for all fields except for lateral steering of 40 mm [Fig. 2(c)] but there was no consistent pattern of increasing error with steering distance
Summary
Ultrasonic transducers used for therapeutic applications employ multiple elements to enable focal steering, and for transcranial applications, in particular, to facilitate aberration correction and focussing in the brain. In order to perform accurate targeting and prediction of the resulting dose to the target tissues, these complex sources and the generated fields must be modelled accurately. Ultrasonic transducers used for therapeutic applications employ multiple elements to enable focal steering, and for transcranial applications, in particular, to facilitate aberration correction and focussing in the brain.. In order to perform accurate targeting and prediction of the resulting dose to the target tissues, these complex sources and the generated fields must be modelled accurately. The most flexible option for defining the source transducer in a model is to characterise the elements under one particular drive condition, and to apply amplitude and phase offsets in simulation to generate different steered, focused, and aberration corrected fields.. Differences have been observed between the output of array elements driven individually compared to when they were driven simultaneously and the output power of a 256-element clinical array transducer was approximately 5% higher when the beam was steered compared to when geometrically focused.
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