Abstract

The solubilities of asiaticoside in water, methanol, ethanol, n-propanol, n-butanol, and a methanol + water mixture were determined over the temperature range from (278.15 to 343.15) K by a static analytical method. The concentrations of asiaticoside in the saturated solutions were analyzed by reverse-phase high-performance liquid chromatography. An “N”-type curve was found for the solubilities of asiaticoside in the methanol + water mixture. Two empirical equations were proposed to correlate the experimental data, which fit the data well.

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