Abstract
BackgroundThis study was aimed to assess the coverage of two doses of measles vaccine and identify the determinants of the delayed vaccination.MethodsA cluster survey among 1386 children aged 24–35 months was conducted. Characteristics on demographic and socio-economic and vaccination records was collected. The overall coverage was defined as the proportion of children receiving the first dose of measles vaccination and the second dose of measles vaccination by 24 months of age. The age-appropriate coverage was defined as the proportion of children receiving the measles vaccine doses within one month after its relevant due date. Timeliness was evaluated with the Kaplan-Meier analysis. Cox proportional hazard regression was adopted to identify determinants of the delayed vaccination.ResultsThe overall coverage was 96.9% for the first dose of measles vaccine and 93.9% for the second dose of measles vaccine. The age-appropriate coverage of the first and the second dose of measles vaccine was 76.6 and 68.2%, respectively. Household having more than one child, non-local children were associated with the delayed vaccination for the first and the second dose of measles vaccine. Children delivered at home, younger mothers, low maternal education background, mothers with a fixed job, and low household income were associated with the delayed vaccination for the second dose of measles vaccine.ConclusionsThe coverage of measles vaccine had been improved for both the first and the second dose, while the timeliness still needed improvement. We suggested the policy-makers pay more attention to the reasons for non-vaccination and determinants of delayed vaccination when planning efforts to ensure the high age-appropriate coverage of measles vaccination.
Highlights
This study was aimed to assess the coverage of two doses of measles vaccine and identify the determinants of the delayed vaccination
Determinants related with delayed measles-containing vaccine (MCV) vaccination Household having more than one child, non-local children were associated with delayed vaccination of both MCV1 and MCV2
Except for these two determinants, Children delivered at home, younger mothers, low maternal education background, mothers with a fixed job, and low household income were associated with delayed vaccination of MCV2 (Table 4)
Summary
This study was aimed to assess the coverage of two doses of measles vaccine and identify the determinants of the delayed vaccination. Measles can be stopped by vaccination with measles-containing vaccine (MCV), which is one of the most cost-effective public health interventions. Due to the highly contagious nature of measles [2], the World Health Organization (WHO) suggests that over 95% of the target population should be immunized with two doses of MCV to halt measles transmission [1]. Missed individuals, vaccinated individuals with primary vaccination failure or immunity waning are susceptible. The secondary attack rate is around 90% among the susceptible population [1]. The second dose of MCV is critical in resolving the primary vaccination failure or boosting the antibody titers after the immunity waning
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