Abstract

Background: Every year, approximately 800,000 people die from liver diseases associated with hepatitis B virus (HBV) infection. Complications outside the liver are common, such as fungal lung infections and viral infections. These complications may be associated with poor immune function, thus making clinical treatment difficult and increasing the risk of death. Therefore, HBV-infection-related liver diseases are worthy of clinical attention and further research. Case summary: We report a case of HBeAg-negative chronic hepatitis B in which the patient received entecavir as an anti-HBV treatment after liver dysfunction. During the treatment, the patient was diagnosed with measles and severe viral pneumonia. After comprehensive treatment, including active antiviral medications and mechanical ventilation, the patient recovered and was discharged. Conclusion: HBV infection causes liver damage, affects immune function, and is likely to be associated with viral infections such as measles. Consequently, infections may lead to complications, such as severe viral pneumonia, that endanger patients’ lives. To decrease complications and mortality, better understanding of the disease is necessary to enable early diagnosis.

Highlights

  • Despite advances in the understanding of the immune pathogenesis of chronic hepatitis B (CHB) in recent years, as well as improvements in diagnosis and treatment methods, CHB remains associated with substantial morbidity and mortality [1,2]

  • hepatitis B virus (HBV) infection causes liver damage, affects immune function, and is likely to be associated with viral infections such as measles

  • Infections may lead to complications, such as severe viral pneumonia, that endanger patients’ lives

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Summary

Conclusion

HBV infection causes liver damage, affects immune function, and is likely to be associated with viral infections such as measles. Infections may lead to complications, such as severe viral pneumonia, that endanger patients’ lives. To decrease complications and mortality, better understanding of the disease is necessary to enable early diagnosis. Edited by: Jian Wu, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, China. Reviewed by: Dawei Cui, The First Affiliated Hospital, Zhejiang University School of Medicine The other reviewer chose to be anonymous. Received: September 03 2021 Revised: October 02 2021 Accepted: December 23 2021 Published Online: January 14 2022

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ETHICS APPROVAL AND CONSENT TO PARTICIPATE
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