Abstract

mean corpuscular volume (MCV) informs a lot about condition of the human body including directly or indirectly signaling about plethora disorders as erythrocytes being an oxygen carrying cells by its indicators’ changes elucidate oxygen content status of the organism. The erythrocytes index parameters particularly MCV can be indicative of the result of the many conditions. In current review the data about MCV variations, namely macro- and microcytosis are systematized and analyzed in further three groups: while physiological conditions of human body (age, sex, pregnancy), in different diseases (variety types of anemias, kidney disorders, endocrine system pathology, cardiovascular disorders, chronic obstructive pulmonary disease) including under the treatment of the latter (antiretroviral treatment of HIV, colorectal cancer, phlebotomy), and caused by iatrogenic influence (toxins, smoking, alcohol drinking). Current minireview includes mindful analysis of 20 trials published in PubMed database.

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