Abstract

Sonographic carotid intima media thickness measurement in diabetic patients is an important tool for estimating the risk of cardiovascular and cerebrovascular events. It is a simple, noninvasive and widely available tool which can give idea of further treatment needed. The objective of this study was to determine the mean intima media complex thickness in patients with type II diabetes mellitus attending a tertiary care center. This was a descriptive cross-sectional study done in 64 patients with the type II diabetes mellitus patients visiting diabetic clinic of Tribhuvan University Teaching Hospital, sent for carotid Doppler examination in the department of radiology and imaging. Ethical approval was taken from the Instituitonal Review Board. Convenient sampling method was used. Carotid intima media thickness was measured on both sides and mean intima media thickness was calculated. Mean intima media thickness for male and female diabetic patients was also calculated separately. Statistical Package for Social Sciences version 25 was used for data analysis. The mean carotid intima media thickness was 0.86±0.13mm with range from 0.7mm to 1.3mm. Mean intima media thickness in male was 0.832±0.094mm and in female it was 0.904±0.144mm. Among 64 patients, 30 (46.8%) were female and 34 (53.3%) were male. Age of the patients ranged from 35 years to 68 years with mean age of 52.4±6.54 years. Carotid intima media thickness in patients with type II diabetes mellitus showed higher values than that of mean value from study done in similar study. Female had higher mean intima media thickness than male.

Highlights

  • Sonographic carotid intima media thickness measurement in diabetic patients is an important tool for estimating the risk of cardiovascular and cerebrovascular events

  • This was a descriptive cross-sectional study done in patients with type 2 Diabetes mellitus visiting the diabetic clinic of Tribhuvan University Teaching Hospital (TUTH) and patients visiting the Department of Radiology and Imaging for carotid Doppler examination

  • Patients with Type 2 Diabetes Mellitus, patients aged more than 25 years and both sexes were included in the study

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Summary

Introduction

Sonographic carotid intima media thickness measurement in diabetic patients is an important tool for estimating the risk of cardiovascular and cerebrovascular events. It is a simple, noninvasive and widely available tool which can give idea of further treatment needed. Intima-media thickness (IMT) is an early marker of atherosclerosis, independent predictor of cardiovascular and cerebrovascular disease and used for effectiveness of medical therapies in treating atherosclerosis. Noninvasive techniques such as B-mode ultrasound can directly assess the IMT, which corresponds to the thickness of the histologic intima and media.[1-3]. IMT is considered to correlate well with the duration of diabetes and various parameters associated with it.[4-7]

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